2000 3.4L 4runner missing

Recently my 4runner stared missing. I thought it was bad gas but have been through a tank and a half a a bottle of seafoam and it is still missing. It is very noticeable at low RPM. It has a loss of power until it drops a gear when accelerating. Does use more gas. Is this a spark plug/ wires problem or a fuel delivery problem.
P.S. it started when I cranked up one day. It ran fine before that crank. Any help is appreciated. Thanks.

 

My miss ended up being a fuel injector. Most recommend the following steps.

-Plugs and wires

-If that doesn't fix the issues, swap the coils and see if the miss moves.

-If it doesn't move it is most likely a bad injector

 

What cylinder is miss firing?

As Vince said the Injectors are often missed because people will go for that "Oh it needs a tune up first" step first.

As he said move the coils around but keep track of what you moved so you will know. Next pull all the plugs and inspect them, I had one that craced once and I missed it the first look. NOTE!!!!!! Don't be that guy who puts the plugs back in the head with out some Anti-Seize, Go to the local parts house and get some it is cheap and far cheaper to do it correct than mess up the heads. SO many people forget this step and it can end in a real Fing mess! Seen it happen man. Remember that is metal in a aluminum cylinder head.

Next- While you are at the local parts house get a Bottle of Chevron Techron. It's in a black bottle- That stuff WORK and will actually clean an injector. I mix it one bottle too 3/4 tank with 93 octane if I can find it. That clean out my lazy injector I had.

Keep us posed.

Blue